Cell Culture-based Viral Vaccines

Cell Culture-based Viral Vaccines - ESACT Course, 1st Edition

September 21st – 23rd, 2016, Llafranc, Spain

Coordinators: Amine Kamen (McGill University), Yvonne Genzel (Max Planck Institute for Dynamics of Complex Technical Systems) and Francesc Gòdia (Universitat Autonoma de Barcelona)

ESACT (European Society for Animal Cell Technology) offers an introductory intensive course in cell culture produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This course introduces the basic principles of vaccination and manufacturing of viral vaccines. Also, the course will provide an overview of the advanced strategies to respond to the challenges of new and established viral infection diseases. The course has been design to benefit those starting their research activity in this field, both from Academia, Industry or Public Health Agencies. It is also of interest for those wishing to up-date their knowledge and know-how in cell production of viral vaccines.

The course will cover the following topics:

  • Principles of Immunology and virology: classification of viruses, what vaccine elicits what immune response
  • Cell lines for vaccine production: from adherent to suspension and primary to designer cell line
  • Upstream Process development: from batch to high cell density, microcarrier-based or using suspension cells
  • Analytical assays, potency assays, QbD and PAT: how to analyse virus amount, process attributes, purity
  • Downstream Processing: purifying of whole viruses, the burden of host cell protein and DNA
  • Vaccine Formulation: requirements of the different vaccines – from bait to needle or nanopatch

Case studies for special vaccines:

  • Recombinant vaccines: Virus like particles (VLPs) and vectored vaccines
  • Case study: Polio vaccines: overview on history, upstream processing and regulation
  • Case study: Dengue vaccine development Vaccine approaches, clinical studies
  • Case study: Influenza vaccines: pandemic, seasonal vaccine, recombinant to egg-based vaccine
Insights from WHO and Bill and Melinda Gates Foundation.

Confirmed lecturers: Amine Kamen (McGill, Canada), Reingard Grabherr (Boku, Austria),  Leo van der Pol (IntraVac, The Netherlands), Yvonne Genzel (MPI, Germany), Francesc Godia (UAB, Spain), Cristina Peixoto (iBET, Portugal), P. Leung-Tack (Sanofi-Pasteur, France), E.Petiot (Universite Claude Bernard, France), I. Ernest (GSK, Belgium), L. Palkonyay (WHO) and R. Prasad (Bill and Melinda Gates Foundation,US). Other information can be found in www.esact.org.

Download the flyer here.

Registration / Fee

Registration is CLOSED.

Contact / Organization Committee

For details please click here.

Accommodation / Travel Information

For details please click here.


The program can be found here.

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